Course Information
Course Title Code Semester T + P ECTS
Cell and Tissue Engineering BMM417 7 3 + 0 6

Prerequisites None

Language Turkish
Level Bachelor's Degree
Type Area Elective
Coordinator Assoc.Prof. MUHAMMET UZUNTARLA
Instructors
Goals Many studies with a combination of discipline, knowledge accumulation, cell-based therapeutic approaches, biocompatible materials and designs used in tissue architecture and characteristics of the foundation stones of cells, the role of stem cells in this process, along with current practices in the field of tissue engineering products to elicit discussion of ethical approaches.
Contents Analogs of extracellular matrix, extracellular matrix, synthetic polymers, natural polymers, and regulation of cell functions, stem cells, cell adhesion, cell-biomaterial interactions, cellular movement and metabolism, tissue development, tissue modeling, cell and tissue in the mass transfer characteristics, tissue regeneration , angiogenesis, drug release, immune protection, inflammation, tissue engineering approaches, induction of tissue (skin, nerves, blood vessels, tendons, ligaments, bone), cell transplantation, biyohibrid organs, blood formation, gene therapy, tissue engineering products; patents, rules
Work Placement(s) Absent

Number Learning Outcomes
1 Can make the definition of tissue engineering products, give examples of them.
2 Can determine identification of the components of Cell microenvironment, the conditions for the cell growth kinetics and control.
3 2-dimensional and 3-dimensional cell culture medium, cell culture medium to express the differences between the cells of biocompatible materials for the transition from the basic properties of tissue identification
4 Can express tissue dynamics of stem cells and tissue engineering application areas.
5 Can express connective tissue, nervous tissue, the cardiovascular system, such as engineering samples what they have learned about the samples together with the elements of ethics.

Mode of Delivery Face-to-Face
Planned Learning Activities & Teaching Methods Theoretical lectures, discussion
Assessment Methods Midterm Exam, final exam



Course Content
Week Topics Study Materials
1 Cell and tissue engineering, cell-based therapeutic approaches, and ethical debates Read on the subject.
2 Tissue dynamics analysis, tissue and cell homeostasis and cellular mechanisms of signal components Read on the subject.
3 Extracellular matrix components, and similar materials, tissue engineering Read on the subject.
4 Identification of extracellular matrix components and biocompatible materials Read on the subject.
5 Sources identified Cell, cell culture techniques and cell differentiation: The importance of tissue engineering types of 2D and 3D culture Read on the subject.
6 Representation of Using the potential of stem cells in tissue engineering Read on the subject.
7 Tissue engineering architecture Read on the subject.
8 Controlled release strategies Read on the subject.
9 Midterm Exam Read on the subject.
10 Skin tissue engineering Read on the subject.
11 Cartilage tissue engineering Read on the subject.
12 Bone tissue engineering Read on the subject.
13 Neural tissue engineering Read on the subject.
14 Ethical issues in tissue engineering and organ systems Read on the subject.



Sources
Textbook Robert Lanza, Principles of tissue engineering, 3rd edition
Additional Resources Robert Lanza, Principles of tissue engineering, 3rd edition



Assessment System Quantity Percentage
In-Term Studies
Mid-terms 1 100
In-Term Total 1 100
Contribution of In-Term Studies to Overall 40
Contribution of Final Exam to Overall 60
Total 100





Course's Contribution to PLO
No Key Learning Outcomes Level
1 2 3 4 5
1 Has principal knowledge about Math, Science and Engineering subjects related to their own branches. x
2 Uses Math, Science and theoretical and practical knowledge of their own areas to find solutions for current engineering problems. x
3 Identifies, formulates and solves engineering problems, for that purpose, selects and applies appropriate analytical methods and modeling techniques. x
4 Analyzes a system, a component, or a process, designs under realistic constraints to meet the desired requirements; implements the methods of modern design accordingly. x
5 Selects and uses modern techniques and tools necessary for engineering applications. x
6 Designs and performs experiments, collects data, analyzes and interprets the results. Finds solutions to problems in the fields of medicine and biology using engineering techniques. x
7 Works effectively as an individual and multidisciplinary teams. x
8 Collects information and does research of resources for this purpose, uses databases and other information resources. x
9 Is aware of necessity of lifelong learning; monitors developments in science and technology and continuously renews himself/herself. x
10 Uses informatics and communication technology with computer software that is minimum required by the European Computer Driving Licence Advanced Level. x
11 Communicates effectively verbal and written, uses at least one foreign language at B1 level of European Language Portfolio. x
12 Is aware of universal and social effects of engineering solutions and applications, Is aware of entrepreneurship and innovation and has knowledge of contemporary issues. x
13 Has principal knowledge about professional and ethical responsibility. x
14 Holds awareness about project management, workplace practices, employee health, environmental and occupational safety; and about the legal implications of engineering applications. x
15 Trains individuals to be preferred in biomedical industry by national and international institutions and have the qualification of hardware. x
16 Provides training and consulting services to improve the quality and reliability in the use of technology in hospitals in the field of clinical engineering. x
17 Provides consulting and technical support services to hospitals, health organizations and medical technology manufacturers/sellers. x



ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
Activities Quantity Duration (Hour) Total Work Load (h)
Course Duration 14 3 42
Hours for off-the-classroom study (Pre-study, practice) 14 4 56
Assignments 6 2 12
Mid-terms 1 25 25
Final examination 1 30 30
Total Work Load (h) 165
Total Work Load / 30 (h) 5.5
ECTS Credit of the Course 6